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Eating Disorders Genetics Initiative 2

Eating Disorders Genetics Initiative 2

Recruiting
12-99 years
All
Phase N/A

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Overview

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Eligibility

Inclusion Criteria:

  • A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms
  • Age 12-99 years, depending on country. (US enrollment age is 18-99)

Exclusion Criteria:

  • History of subthreshold disordered eating behaviors.

Study details
    Anorexia Nervosa
    Bulimia Nervosa
    Binge-Eating Disorder
    Avoidant Restrictive Food Intake Disorder

NCT06594913

University of North Carolina, Chapel Hill

12 September 2025

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