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Study of Brain-spinal Cord Neural Connectivity in Spasticity

Study of Brain-spinal Cord Neural Connectivity in Spasticity

Recruiting
3-17 years
All
Phase N/A

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Overview

Little is known about the peripheral and central mechanisms of action of selective dorsal rhizotomy surgery for the treatment of spasticity. A better understanding of these mechanisms will enable us to improve the surgical procedure. This will require cortico-medullo-radiculo-muscular recordings never before performed and published in the literature, and the identification of variations in connectivity correlated with the clinic.

Eligibility

Inclusion Criteria:

  • Patients aged 3 to 17 years included
  • scheduled for selective rhizotomy surgery
  • Having received informed consent to participate in the study (written consent from both parents)
  • Affiliated or beneficiary of a social security scheme

Exclusion Criteria:

  • Contraindications to selective rhizotomy
  • History of epilepsy
  • Known neurological and/or psychiatric disorders with past and/or current medical treatment, or drug addiction
  • Patient under legal protection
  • Pregnant or breast-feeding women

Study details
    Spasticity
    Muscle

NCT06281223

Fondation Ophtalmologique Adolphe de Rothschild

12 September 2025

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