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Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study

Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study

Recruiting
15-60 years
All
Phase N/A
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  • Simplified (AI rewritten)

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Overview

Regarding oral cavity cancer, the high incidence of neck metastasis along with its impact on survival and prognosis are in favor of elective neck dissection. Moreover, occult metastases could develop at lower levels in the neck (levels IV-V) Regarding the tongue, the rate of skip (occult) metastasis involving unremoved level IV cervical lymph nodes in squamous cell carcinoma of the tongue ranges from 0 % - 11.4 %. However, no data is available or a correlation between the risk of level IV involvement and the affection of specific tongue subsites or a certain cutoff value of tumor thickness.

Eligibility

Inclusion Criteria:

  • Patients with squamous cell carcinoma of the tongue and floor of the mouth.
  • Age group: from 15 to 60 years old
  • No sex predilection

Exclusion Criteria:

  • Patients with recurrent squamous cell carcinoma of the tongue and floor of the mouth.
  • Irradiated patients or those taking chemotherapy.

Study details
    Tongue Neoplasms

NCT06169605

Cairo University

14 October 2025

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