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Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD

Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD

Recruiting
10-17 years
All
Phase N/A

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Overview

The goal of this clinical trial is to learn if self-help book can be used to treat obsessive-compulsive disorder (OCD) in adolescents aged 10 to 17. The main questions it aims to answer are:

Can adolescents and their parents effectively reduce the severity of the obsessive-compulsive symptoms in adolescents who are already stably taking medications through self-help books? What are the characteristics of adolescents who are best suited to use self-help intervention book to treat obsessive-compulsive symptoms?

Researchers will compare the use of a self-help books plus medication with medication alone to see if the combination of the self-help intervention and drug treatment can improve the obsessive-compulsive symptoms of adolescents more effectively.

Participants will:

  • Read one chapter of a self-help book and complete the corresponding exercise each week for 12 weeks
  • Visit the clinic before and after intervention for checkups and tests

Eligibility

Inclusion Criteria:

  1. Age between 10 and 17 years
  2. Satisfied with the diagnostic criteria for OCD in DSM-5
  3. 16≤CY-BOCS score ≤23
  4. Taking medication stably for 6 weeks
  5. Education level ⩾6 years
  6. At least one parent can accompany the patients throughout the entire intervention process
  7. The patient and the participating parent have sufficient reading and writing skills to complete the treatment intervention
  8. The patient and the participating parent have adequate auditory and visual abilities skills to complete the necessary examinations for the study

(7) Right-handed (this criterion is for fMRI subjects only) (8) Subjects and their guardians understood the study and signed informed consent.

Exclusion Criteria:

  1. Obsessive-compulsive symptoms were too severe to participate in the experiment(CY-BOCS score ≥24)
  2. High risk of suicide
  3. Comorbid brain organic diseases, severe somatic diseases, learning disabilities, autism spectrum disorders, schizophrenia spectrum and other psychotic disorders, bipolar disorder, severe eating disorders, or substance abuse
  4. Completed a Cognitive Behavioral Therapy (CBT) course for OCD within the past 12 months.
  5. An IQ lower than 80
  6. Currently undergoing other psychological/physical treatments
  7. Uncooperative or unable to complete treatment
  8. With metal implants in the body, such as pacemakers, intracranial silver clips, metal dentures, arterial stents, arterial clips, joint metal fixation, or other metal implants, etc. (this criterion is for fMRI subjects only)

Study details
    Obsessive - Compulsive Disorder

NCT06942494

Shanghai Mental Health Center

10 September 2025

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