Overview
Patients admitted for polytrauma, severe neurological injury, post-operative monitoring or sepsis/septic shock present with significant inflammation, leading to immunoparalysis, which is responsible for infection, particularly prolonged infection. A study of their lymphocyte phenotype over time could help explore the phenomenon of immunoparalysis.
Eligibility
Inclusion criteria:
- Postoperative esophagectomy surveillance within the last 24 hours.
- Patients with intra-abdominal infection
- Neurological patients with intubation planned for more than 24 hours (subarachnoid hemorrhage with coma, severe head trauma, ischemic or hemorrhagic stroke with coma).
- Polytrauma with intubation planned for more than 24 hours
- Patient aged 18 and over
- Patient with social security coverage
Non-inclusion criteria :
- Hereditary immune deficiency HIV-AIDS
- Malignant hemopathies
- Immunosuppressive treatment other than corticosteroid therapy or chemotherapy
- Patient under legal protection
- Pregnant or breast-feeding women