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Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor

Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this observational study is to evaluate the feasibility and clinical utility of radiomics to diagnose peri-lesion tumour infiltration of tumours in participants with a suspect of Bone Cancer Tumor or Soft Tissue Sarcoma (STS).

The main questions it aims to answer are:

  • is radiomics able to identify the ratio of participants truly diagnosed as positive to all those who had positive test results?
  • is radiomics able to identify the likelihood that a participant who has a negative test result indeed does not have the disease?

Participants eligible for this study will get a MRI as part of their regular medical care. The only difference is that their data will be recorded and anonymously analyzed.

Eligibility

Inclusion Criteria:

  • Age over 18
  • suspect of soft tissue sarcoma with a indication for surgical treatment
  • suspect of bone cancer tumor with a indication for surgical treatment
  • To give informed consent

Exclusion Criteria:

  • simultaneous cancer or history of cancer in the last 5 years
  • acute or chronic serious conditions that could
  • contraindication to conduct a Contrast-enhanced magnetic resonance imaging (MRI) such as:
    • renal failure without dialysis
    • history of allergy to a paramagnetic contrast agent
    • claustrophobia
    • symptomatic epilepsy or history of epilepsy
    • cardiac pacemaker
    • infusion pump, prosthesis or any implant not compatible with MRI
    • pregnancy

Study details
    Soft Tissue Sarcoma (STS)
    Bone Cancer Tumor

NCT06774729

IRCCS Azienda Ospedaliero-Universitaria di Bologna

9 September 2025

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