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Dural Arteriovenous Fistulas Research at China INI

Dural Arteriovenous Fistulas Research at China INI

Recruiting
18-80 years
All
Phase N/A

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Overview

Dural arteriovenous fistula (DAVF) refers to abnormal connections between meningeal arteries and dural venous sinuses and/or subarachnoid veins. DAVF accounts for approximately 10% to 15% of intracranial vascular malformations. With advancements in imaging technology, increased awareness among physicians, and an aging population, the incidence of DAVF appears to be on the rise. Some literature even suggests it may surpass the occurrence of arteriovenous malformations. Several large-scale retrospective studies have been conducted internationally, involving over 1,000 cases, but some of their findings differ from what is commonly understood. Currently, there is a lack of large-sample single-center studies on DAVF, highlighting the urgent need for such research.

Description

Title:Dural Arteriovenous Fistulas Research at China INI.

Purpose:The incidence of DAVF is low. By collecting clinical data, we aim to establish a comprehensive database and biobank. This will help us elucidate the potential pathogenesis, vascular architecture, biological markers, and treatment outcomes of DAVFs. Furthermore, this study aims to address current controversies (such as treatment strategies for DAVF with pial arterial supply), unresolved issues (such as the optimal treatment and prognosis of infantile type DAVF), and further explore possible mechanisms of DAVF development.

Eligibility

Inclusion Criteria:

  • Adult patients with DAVFs who were admitted to Xuanwu Hospital.

Exclusion Criteria:

  • Non-DAVF lesions confirmed by DSA.

Study details
    Fistula

NCT06543472

Xuanwu Hospital, Beijing

14 October 2025

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