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Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor

Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor

Recruiting
18 years and older
All
Phase N/A
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Overview

This study will test the feasibility and effectiveness of an innovative model of care for cognitively impaired patients with heart failure. This program aims to improve cognition, reduce dementia risk and cardiovascular events, and will be supported by innovative digital technology for wide scale rollout and implementation. Findings from this research will transform the way healthcare is delivered to cognitively impaired patients with heart disease who have a very high risk of developing dementia.

Eligibility

Inclusion Criteria:

  1. Hospitalised with HF as primary or secondary diagnosis.
  2. At least mild cognitive impairment (CI) based on Montreal Cognitive Assessment (MoCA) on hospital discharge.

Exclusion Criteria:

  1. Unable to provide written consent; requiring palliative care; or participating in another RCT
  2. Recovery of cognitive function shortly after hospital discharge: to ensure that we only include patients with "true" CI, any patients with a repeated MoCA>25 at 2 weeks post-discharge will be excluded.
  3. Terminal illness (eg. cancer) that may influence 12-month prognosis.

Study details
    Heart Failure
    Cognitive Impairment
    Dementia
    Left Ventricular Dysfunction
    Cognitive Change
    Cognitive Decline

NCT06088212

Baker Heart and Diabetes Institute

6 September 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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