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Mood And Kids diEt (MAKE-It) Pilot Trial

Mood And Kids diEt (MAKE-It) Pilot Trial

Recruiting
11-17 years
All
Phase N/A

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Overview

This study is being done to examine the feasibility, including recruitment, retention and acceptability of a randomized controlled trial of a personalized dietary intervention in adolescents with depression. Evidence suggests that dietary quality may affect an individual's mood. A healthy diet includes vegetables, fruit, nuts, seeds, and olive oil, as well as minimally processed whole grains, legumes, and moderate amounts of lean meat, fish, and dairy.

The investigators will examine the feasibility of testing a personalized nutrition eating plan in a study that uses a randomized controlled trial design for children and youth with depression.

Eligibility

Inclusion Criteria:

  • diagnosis of MDD
  • Center for Epidemiological Studies Depression Scale for Children (CESD-C) score ≥ 25 at baseline
  • access to the internet and a computer or smart phone
  • presence of a parent who is willing to participate

Exclusion Criteria:

  • adherent to a high-quality diet at baseline
  • presence of an eating disorder
  • currently participating in other dietary programs or studies
  • actively attempting to increase or decrease body weight;
  • presence of a chronic medical condition;
  • unstable psychiatric condition (e.g., mania, active suicidal ideation)

Study details
    Depression - Major Depressive Disorder
    Adolescent

NCT06716034

The Hospital for Sick Children

5 September 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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