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The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients

The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients

Recruiting
18 years and older
All
Phase 3
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Overview

This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.

Description

This study will be a randomized controlled trial involving high-risk patients undergoing open repair of primary elective groin hernias. Participants will be randomized into two groups: one receiving antibiotic prophylaxis and the other serving as the control group. The study will assess the incidence of wound infections postoperatively in both groups to determine the effectiveness of antibiotic prophylaxis in lowering infection rates.

Eligibility

Inclusion Criteria:

  • Volunteer to participate in the study.
  • Elderly patients aged over 60 years.
  • Patients with Diabetes.
  • Or obese patients with a BMI greater than 35.
  • Or immunocompromised patients.
  • Or American Society of Anesthesiologists (ASA) physical status classification 2 or more, with a history of more than 10 years.

Exclusion Criteria:

  • Non-cooperative patients for regular follow-up.
  • Therapeutic Indication for.

Study details
    Antibiotic Prophylaxis
    Wound Infection
    Groin Hernia

NCT06576154

University of Aleppo

14 October 2025

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