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Observing Physiological Changes in Patients With Long-term Oxygen Therapy

Observing Physiological Changes in Patients With Long-term Oxygen Therapy

Recruiting
18 years and older
All
Phase N/A

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Overview

In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life.

For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.

Eligibility

Inclusion Criteria:

  • Age ≥ 18-year-old, and
  • Chronic respiratory disease including a) chronic obstructive pulmonary disease, b) interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and
  • Prescribed new LTOT due to a chronic respiratory disease with resting and/or exertional hypoxemia, and
  • Able to speak/read/understand German or French, and
  • Willing and able to understand and provide signed informed consent

Exclusion Criteria:

  • Pregnant or lactating women, or
  • Inability to follow the procedures/instructions of the study (e.g. due to language, psychological disorders, dementia, etc.), or
  • Patients having a subordination link to the investigators, or
  • Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heart disease, sleep associated breathing disorder, neuromuscular disease or lung cancer, or
  • Known participation in another human research project (ClinO/HRO) that may affect the objectives of this study.

Study details
    Chronic Respiratory Disease

NCT06525857

Insel Gruppe AG, University Hospital Bern

4 September 2025

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