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A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study

A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study

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Overview

The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period. The main questions it aims to answer are:

  1. Are these novel implants safe, effective, and clinically viable for 36 months?
  2. Do these drilling-free implants result in better post-operative outcomes compared to traditional implant techniques? Twelve patients receiving these customized implants immediately after tooth extraction will undergo clinical and radiographic examinations at 12, 24, and 36 months after prosthesis installation. The study will assess peri-implant tissue health, post-operative comfort, bone preservation, tissue integration, and implant survival rates.

Eligibility

Inclusion Criteria:

  • Received a personalized dental implant using the iDENTICAL Dental Implant System during the previous interventional phase;
  • Completed the 12-month follow-up period after implant placement in the previous interventional phase;
  • Available for follow-up evaluations during the 36 months of the observational study.

Exclusion Criteria:

  • Occurrence of serious complications (implant loss, infection, etc.) during the previous interventional phase;
  • Development of uncontrolled medical conditions during the follow-up period;
  • Inability to attend scheduled follow-up visits;
  • Refusal to participate in the observational study.

Study details
    Tooth Loss
    Dental Implant

NCT06576284

University of Sao Paulo

2 September 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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