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Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Recruiting
18 years and older
All
Phase N/A

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Overview

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Eligibility

Inclusion Criteria:

  • Able to consent
  • Age 18 years or older
  • Diagnosis of COPD
  • Ability to ambulate without assistance
  • Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all

Exclusion Criteria:

  • Pregnancy
  • Being on bedrest
  • Inability to consent or cooperate with the study
  • Using of > 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
  • Hemodynamic instability (resting heart rate > 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
  • Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)

Study details
    COPD

NCT06578156

University of Miami

31 August 2025

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