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Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

Recruiting
18-55 years
Female
Phase 2
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Overview

The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D&E) in the clinic setting.

Eligibility

Inclusion Criteria:

  • clinic-based D&E at 18 weeks gestational age and above
  • speaks English or Spanish

Exclusion Criteria:

  • refuses IV
  • history of coagulopathy
  • anticoagulant use in the preceding five days
  • chorioamnionitis or sepsis
  • suspected placenta accreta spectrum
  • intrauterine fetal demise
  • multiple gestation
  • use of misoprostol for cervical preparation

Study details
    Hemorrhage

NCT06141447

University of Colorado, Denver

31 August 2025

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