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Virtual perI-/Menopause Registry of AusTrALia

Virtual perI-/Menopause Registry of AusTrALia

Recruiting
18 years and older
All
Phase N/A

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Overview

13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, & all such who live to midlife will experience menopause, defined as >12 months without a period. Peri-menopause (peri), typically occurs 5 yrs before menopause as hormone levels decrease. As with oestrogen, peri symptoms can affect every bodily system; e.g. depression/anxiety, diminished mental function, irregular periods, hot flushes, sleep problems, vaginal atrophy & urinary urgency. These symptoms are linked with lower quality of life & significantly higher work impairment; a third experiencing symptoms so severe as to impede daily life & increase risk of suicide. Lifetime increased risks of diabetes, heart disease, osteoporosis & dementia are also associated with menopause, yet it remains disconcertingly poorly studied.

The investigators propose to create a world-first, cutting-edge, consumer-driven, Virtual peri-/menopause registry of AusTrALia (VITAL). The unique design will enable consumers to determine VITAL's questions, encourage secure revelation of private data e.g. vaginal & mental health symptoms, & to direct priorities for research, education, & health service improvements. VITAL will thus deliver optimal assessments of incidence, prevalence & impact.

The participating consumers, researchers, clinical specialists, policy makers, & modern virtual data infrastructure enable this unique & innovative registry design, future translation to improved community health, & promote awareness & collaborative synergies. Leveraging the investigators' critical range of expertise & ongoing feedback opportunities for both participants & stakeholder partnerships, the investigators will create a ground-breaking platform that:

  • empowers the consumer voice and priorities,
  • enables peri-/menopause research to extend beyond existing niche focuses,
  • evidences the true impact of peri-/menopause across the nation,
  • evolves healthcare services and outcomes, &
  • educates community, clinicians, & policy-makers. After Australian registry establishment, the investigators will expand VITAL to mirror it in other nations while still protecting individual's data the right way, but so all can learn & apply the best aspects of care from across the world.

Description

In the Virtual Peri-Menopause Registry of Australia -VITAL- the investigators will:

  1. Co-create an innovative, multidisciplinary, ongoing digital epidemiological platform & repository of Australian peri-/menopausal health, centred on relevance to the community;
  2. Establish incidence, prevalence & impact of Australian peri-/menopause symptomology, associated disease risk factors, & healthcare system pathways, via secure participant input, encouraging safe revelation of personal data, e.g. symptoms, impairment, substandard care;
  3. Determine & define community consensus priorities in related healthcare & associated policy.
  4. Disseminate not only results, but ensure accessibility of the data from the national registry to authorised, relevant & ethical investigations to streamline research & in turn, translate to community healthcare outcomes, e.g. community education, clinical advice, policies, data linkage with significant datasets and/or registries e.g. cardiac, cancer, ageing, Medicare etc.

Eligibility

Inclusion Criteria:

  • Any Australian over 18 years of age.

Exclusion Criteria:

  • None.

Study details
    Menopause
    Perimenopausal Disorder
    Postmenopausal Symptoms
    Health Knowledge
    Attitudes
    Practice
    Healthy Aging
    Health Care Utilization
    Health Care Seeking Behavior
    Mental Health Impairment
    Mental Deterioration
    Mental Health Issue
    Osteoporosis
    Postmenopausal
    Diabetes Mellitus Risk
    Diabetes Mellitus
    Type 2
    Dementia
    Cardiovascular Diseases
    Menopause Related Conditions
    Hot Flashes
    Hot Flushes Aggravated
    Economic Burden
    Social Stigma

NCT06487130

Bespoke Clinical Research

31 August 2025

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