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TumorGlow Intraoperative Molecular Imaging (IMI)

TumorGlow Intraoperative Molecular Imaging (IMI)

Recruiting
18 years and older
All
Phase 1/2

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Overview

This is a Phase 1/2 study in patients presenting with any solid tumor and/or diseased tissue even benign nodules presumed to be resectable and at risk for recurrence on pre-operative assessment who are considered to be good surgical candidates to evaluate the safety and efficacy of the image-guided surgery using indocyanine green for intramolecular imaging of solid tumors.

Eligibility

Inclusion Criteria:

  • Adult patients 18 years of age or older.
  • Patients presenting with any solid tumor and/or diseased tissue even benign nodules presumed to be resectable and at risk for recurrence on pre-operative assessment.
  • Good operative candidate as determined by the treating physician and/or multidisciplinary team.
  • Subject capable of giving informed consent.

Exclusion Criteria:

  • Subject unable to participate in the consent process.
  • Vulnerable population including pregnant women, prisoners, and children.
  • History of uncontrolled hypertension (e.g., history of an ER admission for hypertensive crisis or ≥ 3 blood pressure medications)
  • Patients with a self-reported history of iodide allergies.

Study details
    Tumor
    Solid

NCT04723810

University of Pennsylvania

30 August 2025

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