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Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer

Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer

Recruiting
18-80 years
All
Phase N/A

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Overview

Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.

This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients.

A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.

Eligibility

Inclusion Criteria:

  1. The patient was diagnosed with gastric cancer by pathological biopsy
  2. No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
  3. No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.

Exclusion Criteria:

  1. The image quality cannot meet the diagnostic criteria;
  2. Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.

Study details
    Gastric Cancer

NCT06735105

Yunnan Cancer Hospital

14 October 2025

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