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Conventional Spinal Anaesthesia Versus Fractional Spinal Anaesthesia on Hemodynamics

Conventional Spinal Anaesthesia Versus Fractional Spinal Anaesthesia on Hemodynamics

Recruiting
60 years and older
All
Phase N/A

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Overview

compare the systemic haemodynamic response to fractional spinal anaesthesia versus conventional spinal anaesthesia , in a group of elderly and comorbid patients with hip fracture.

Description

Spinal anaesthesia affects sympathetic chain activity, leading to a reduction in vasomotor tone.It was found that the incidence of hypotension following single-shot spinal anaesthesia, has previously been described as being 28-69%. As a matter of fact, autonomic nervous system function plays a key role in the development of haemodynamic instability and intraoperative hypotension . Haemodynamic stability should be considered as a primary intraoperative target, since several findings suggest avoiding systemic pressure drops . It was found that hypotension is primarily related to the overall dose injected ; however, several other variables, including the volume, the type of the anaesthetics injected, different adjuvant agents, and pre- and intraoperative factors, may impact the haemodynamic effect of the SA.

Eligibility

Inclusion Criteria:

  • Patients with hip fractures.
  • Patients age >60 years old.
  • ASA ≤ 3.

Exclusion Criteria:

  • Patients on anticoagulant medication.
  • Planned for general anaesthesia .
  • Patients had atrial fibrillation.

Study details
    Hip Fractures

NCT06583213

Ain Shams University

27 August 2025

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