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Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

Recruiting
40-75 years
Male
Phase N/A

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Overview

  • The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care:
    • Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines.
    • Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices.
    • The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.

Eligibility

Eligibility Criteria:

  • Receive care within the BJC Health System
  • Have had at least one primary care physician appointment in the calendar year of PSA screening (primary care)
  • Be male
  • Not have a history of prostate cancer
  • Meet one of the following risk criteria:
    • High Risk for Prostate Cancer
      • African American, between the ages of 40 and 75 (inclusive), or
      • Family history of prostate, breast, ovarian, and/or pancreatic cancer, or
      • Known familial germline mutation OR
    • Average Risk for Prostate Cancer
      • Between the ages of 50 and 75 (inclusive)

Study details
    Prostate Cancer
    Cancer of the Prostate

NCT07109427

Washington University School of Medicine

27 August 2025

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