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Prospective Analysis of Circulating Nucleosomes in Patients Receiving a First Line Treatment for a Non-Hodgkin Lymphoma

Prospective Analysis of Circulating Nucleosomes in Patients Receiving a First Line Treatment for a Non-Hodgkin Lymphoma

Recruiting
18 years and older
All
Phase N/A
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Overview

The goal of this study is to prospectively follow the level of circulating nucleosomes in patients treated for a non-Hodgkin lymphoma and determine whether it correlates with the clinical response.

Eligibility

Inclusion Criteria:

  • Histologically proven diagnosis of diffuse large B cell lymphoma or follicular lymphoma, according to the WHO 2016 classification, requiring a first line of treatment with a RCHOP 21 regimen
  • Agreement to participate after receiving oral and written information on the study

Exclusion Criteria:

  • History of previous treatment for lymphoma (excluding localized low dose radiotherapy in the case of follicular lymphoma)
  • Treatment with a chemotherapy regimen different from RCHOP21

Study details
    Follicular Lymphoma
    Diffuse Large B-Cell Lymphoma

NCT06813573

Gustave Roussy, Cancer Campus, Grand Paris

26 August 2025

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