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Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars

Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars

Recruiting
15-30 years
All
Phase N/A

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Overview

Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars

Description

Clinical and Radiographic Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF Scaffold in Vital Pulp Therapy in Mandibular First Molars with Closed Apices: "Randomized Controlled Trial"

Eligibility

Inclusion Criteria:

  • Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.
    • Patients of either gender aged from 15-30.
    • Tooth should give positive response to cold test.
    • The tooth is restorable
    • Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
    • Patients who will agree to the consent and will commit to follow-up period.
    • Patients with mature root.
    • Patients with no internal or external resorption and no periapical lesions.
    • Soft tissues around the tooth are normal with no swelling or sinus tract.

Exclusion Criteria:

  • Patients with immature roots.
    • Haemostasias after 10 minutes can not be controlled after total pulpotomy
    • Patients with periapical lesions or infections.
    • Pregnant females.
    • Patients with fistula or swelling
    • Patients with necrotic pulp.

Study details
    Pulpotomy

NCT06640205

Future University in Egypt

23 August 2025

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