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Low-Dose Ketamine Infusion During Burn Wound Care

Low-Dose Ketamine Infusion During Burn Wound Care

Recruiting
18 years and older
All
Phase 4
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.

Eligibility

Inclusion Criteria:

  • Admitted to burn service with thermal injury

Exclusion Criteria:

  • unable/unwilling to consent within 72 hours
  • unable to report NRS
  • known contraindication to ketamine
  • < than 18 years of age
  • pregnant
  • incarcerated
  • TBSA over 50 %

Study details
    Burn
    Pain
    Dissociation
    Opioid

NCT06506565

University of Tennessee

22 August 2025

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