Overview
The aim of this study is to examine the effects of aerobic exercise training using an elliptical trainer compared to a treadmill on gait and walking abilities, expressed in dynamic stability, balance, and walking speed, in people with Multiple Sclerosis with moderate severity.
Description
A total of 30 MS subjects to be enrolled in the study. Subjects to be assigned into one of two groups named: Group 1 - Elliptical Training and Group 2 - Treadmill Training. Effort capacity will measured by heart rate and RPE.
Outcome measures will be measured by using, 6 min. walking test (6MWT), Timed Up & Go (TUG), Berg Balance Scale (BBS) and 10 Meter Walk Test (10MWT) to be used to assess the quality of life at Baseline (T0), During study - 6 weeks from baseline (T1), End of training program - 12 weeks from baseline (T2) and 6 weeks post T2 (T3).
The exercise program to be applied for 12 weeks with 2 trainings per week.
Eligibility
Inclusion Criteria:
- Patients signed Informed Consent Form
- At least 6 months post MS diagnosis
- 25-55 years old adults
- EDSS 3.0-6.5
- Standing stability - for at least 30 seconds
- 6MWT - minimal distance to be measured as 210 meters
- No physical routinely training e.g. walking, elliptical or cycling within 3 months prior screening visit.
Exclusion Criteria:
- Active Heart Disease
- Lungs and/or respiratory system diseases
- Metabolic Disease
- Any other medical condition(s) which might impact the patient's participant in the study, as per PI medical judgement
- Major medical treatment change (as per PI medical judgement) up to 12 weeks prior ICF signature by the patient.