Overview
The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are:
- Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers?
- Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.
Eligibility
Inclusion Criteria:
- Nulliparous women
- Age 18 years or older and able to provide informed consent
- Singleton pregnancy at term
- Induction of labor
- Cephalic presentation
- Unfavorable cervix (Bishop score ≤ 6)
Exclusion Criteria:
- Age under 18 years
- Involuntarily confined or detained
- Considered as having diminished decision-making capacity
- Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned
- Favorable cervix (Bishop score >6)
- Diabetes mellitus (both gestational and pre-gestational)
- Structural renal disease
- Acute or chronic kidney disease resulting in abnormal creatinine or proteinuria
- Evidence of chorioamnionitis or non-reassuring fetal testing at the time of enrollment
- Pyrexia (>38.0 degrees Celsius)
- Stillbirth
- Planned cesarean delivery
- Women presenting with emergent circumstances for labor induction