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Impact of Surgical Position on Stone-Free Rates in Retrograde Intrarenal Surgery

Impact of Surgical Position on Stone-Free Rates in Retrograde Intrarenal Surgery

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this clinical trial is to determine whether the surgical position during retrograde intrarenal surgery (RIRS) affects stone-free rates in adults with kidney stones. The main questions it aims to answer are:

  • Does the modified lithotomy position result in a higher stone-free rate compared to the standard lithotomy position?
  • Are there differences in complication rates between the two surgical positions?

Researchers will compare patients undergoing RIRS in the standard lithotomy position to those in the modified lithotomy position (30-degree Trendelenburg with elevated surgical side) to assess its impact on stone clearance and surgical outcomes.

Participants will:

  • Be randomly assigned to one of two surgical positions
  • Undergo RIRS with standard surgical procedures
  • Have follow-up imaging to assess stone clearance after surgery

This study aims to improve surgical techniques and patient outcomes in kidney stone treatment.

Eligibility

Inclusion Criteria:

  • Presence of single or multiple kidney stones, with the largest stone ≤2 cm
  • Age ≥18 years
  • Provided written informed consent to participate in the study
  • Indicated for retrograde intrarenal surgery (RIRS) as a treatment approach

Exclusion Criteria:

  • Severe cardiovascular disease (e.g., heart failure)
  • Congenital kidney anomalies (e.g., horseshoe kidney, ectopic kidney)
  • Concurrent ureteral stones
  • Pregnancy or planning pregnancy
  • History of previous kidney surgery on the same side
  • Active urinary tract infection (UTI)
  • Coagulopathy or use of anticoagulant therapy that cannot be stopped before surgery

Study details
    Stone
    Kidney
    Stones
    Kidney
    Stone;Renal

NCT06809582

Ondokuz Mayıs University

17 August 2025

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