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A Phase II Clinical Study to Evaluate the Efficacy and Safety of Technetium [99mtc]-H7ND Injection in the Diagnosis of Peritoneal Metastasis of Gastrointestinal Malignant Tumor.

A Phase II Clinical Study to Evaluate the Efficacy and Safety of Technetium [99mtc]-H7ND Injection in the Diagnosis of Peritoneal Metastasis of Gastrointestinal Malignant Tumor.

Recruiting
18 years and older
All
Phase 2

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Overview

The main purpose of this study is to evaluate the effectiveness of technetium [99mTc]-H7ND injection in the diagnosis of peritoneal metastasis of gastrointestinal malignant tumor. Objective: To evaluate the safety of technetium [99mTc]-H7ND injection in the diagnosis of peritoneal metastasis of gastrointestinal malignant tumor. Objective: To explore the diagnostic threshold of technetium [99mTc]-H7ND injection for peritoneal metastasis of gastrointestinal malignant tumor.

Eligibility

Inclusion Criteria:

Only those who meet all the following requirements are eligible to join the group:

  1. Adults over 18 years of age (based on the time when the informed consent form was signed) can be male or female;
  2. Subjects with gastrointestinal malignant tumor confirmed by histology/cytology;
  3. Subjects to be surgically removed or explored;
  4. The estimated survival time is ≥12 weeks;
  5. Subjects of childbearing age agreed to adopt effective contraceptive measures during the study period;
  6. Subjects fully understand the purpose, nature, methods and possible adverse reactions of the experiment, voluntarily participate in and sign a written informed consent, and are willing to follow the requirements of the protocol to complete the study.riteria:

Those who meet one of the following items are not allowed to join the group:

  1. According to the researcher's judgment, during the screening period, from the imaging examination to the comprehensive real diagnosis information result, the patients were treated with anti-digestive tract tumor;
  2. symptomatic brain metastases who need treatment;
  3. Have serious cardiovascular and cerebrovascular diseases;
  4. There are other contraindications for imaging examination of the research plan, such as claustrophobia;
  5. Have a history of other malignant tumors;
  6. Pregnant (pregnancy test positive in screening period) or lactating women;
  7. Other circumstances that the researcher considers inappropriate to participate in this clinical trial.

Study details
    Solid Tumor
    Peritoneal Metastasis

NCT07107633

Jiaxing Pharmadax Genesis Pharmaceutical Technology Co.,Ltd.

11 August 2025

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