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A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers

A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers

Recruiting
18 years and older
All
Phase N/A

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Overview

The aim of this French multicenter retrospective study is to describ rare primary hepatic cancers clinical, histological and radiological features, to obtain a biological tumor and blood collection, and to evaluate the efficacy of treatments received in clinical practice in order to determine optimal therapeutic sequences. This retrospective cohort will be the backbone of future translational studies aimed at identifying new molecular, histological, circulating and radiological tumor biomarkers, potentially useful at every stage of diagnosis and prognostic or theranostic evaluation.

Description

The aim is to describ rare primary hepatic cancers clinical, histological and radiological features, to obtain a biological tumor and blood collection, and to evaluate the efficacy of treatments received in clinical practice in order to determine optimal therapeutic sequences.

Eligibility

Inclusion Criteria:

  • 18 years of age or older,
  • with histologically proven hepato-cholangiocarcinoma, fibrolamellar hepatocellular carcinoma, epithelioid hemangioendothelioma or hepatic angiosarcoma
  • diagnosed after January 01, 2018 living or deceased at the time of registration in the cohort
  • for living patients who have not objected to the research: (note of non-objection to be attached° agreeing to participate in ancillary studies must sign the biological consent form for participation in biological studies.

Exclusion Criteria:

  • without social security
  • No access to tumor block

Study details
    Hepatocholangiocarcinoma
    Fibrolamellar Carcinoma
    Hepatic Epithelioid Hemangioendothelioma
    Hepatoblastoma
    Hepatic Neuroendocrine Carcinoma
    Hepatic Carcinosarcomas
    Hepatic Cystadenoma
    Hepatic Leiomyosarcomas
    Hepatic Angiosarcomas
    Cholangiocarcinoma

NCT06541652

Federation Francophone de Cancerologie Digestive

11 August 2025

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