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Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer

Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer

Recruiting
18-75 years
Female
Phase N/A

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Overview

Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer

Description

This is a Phase II Randomised Controlled Clinical Trial to evaluate the efficacy of auricular acupuncture therapy via the Seirin Pyonex Needles in the prevention of chemotherapy-induced peripheral neuropathy in breast cancer.

Eligibility

Inclusion Criteria:

  • Patients with breast cancer diagnosed with stage I-III;
  • Planned to receive 4 cycles of taxane chemotherapy and have not taken neurostable drugs within three months;
  • 18 years old≤ age≤ 75 years old, female;
  • Subjects voluntarily participate in this trial and sign the informed consent form.

Exclusion Criteria:

  • Patients who have had acupuncture treatment in the past;
  • After examination by a doctor, there is a local infection at or near the acupuncture site, which is not suitable for acupuncture.
  • Platelets< 50,000/μL;
  • Patients with CIPN≥1 grade 1 (NCI-CTCAE);
  • Peripheral neuropathy or other neuropathic pain caused by diabetes mellitus or other factors related to HIV infection.

Study details
    Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer

NCT07092111

The First Affiliated Hospital with Nanjing Medical University

4 August 2025

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