Overview
Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
Description
This is a Phase II Randomised Controlled Clinical Trial to evaluate the efficacy of auricular acupuncture therapy via the Seirin Pyonex Needles in the prevention of chemotherapy-induced peripheral neuropathy in breast cancer.
Eligibility
Inclusion Criteria:
- Patients with breast cancer diagnosed with stage I-III;
- Planned to receive 4 cycles of taxane chemotherapy and have not taken neurostable drugs within three months;
- 18 years old≤ age≤ 75 years old, female;
- Subjects voluntarily participate in this trial and sign the informed consent form.
Exclusion Criteria:
- Patients who have had acupuncture treatment in the past;
- After examination by a doctor, there is a local infection at or near the acupuncture site, which is not suitable for acupuncture.
- Platelets< 50,000/μL;
- Patients with CIPN≥1 grade 1 (NCI-CTCAE);
- Peripheral neuropathy or other neuropathic pain caused by diabetes mellitus or other factors related to HIV infection.