Overview
Reality-monitoring is a crucial cognitive process in daily life to remember the source of an information. Deficits of reality-monitoring have been shown into the continuum of schizophrenia, suggesting a preexisting alteration in population at-risk for psychosis that will be exacerbated during psychotic transition. It is admitted that stress plays a crucial role in the psychotic transition and can alter cognitive performances. However, less is known about the effects of stress on reality-monitoring, even though this process appears to be central in psychotic disorders.
The aim of this project is to investigate the effect of stress on reality-monitoring, both on behavioral and neurophysiological aspects
Description
Forty healthy subjects will be included in the study. Participants will be subject to a standardized stress protocol, half of them receiving an active stress and the other half receiving a placebo. All participants will also complete a reality-monitoring task, electrophysiological (EEG) recordings as well as socio-demographic and psychometric evaluations
Eligibility
Inclusion Criteria:
- Right-handed Men and Women aged between 18 and 30
- Having given their written informed consent
- For women: oral contraceptive use
- French speakers and readers
Exclusion Criteria:
- Do not consent to be included in the study
- Smokers
- Night workers
- Having visual or hearing impairments that could prevent the successful completion of tasks involving reading or listening to sounds
- Taking drug treatment (except oral contraceptive)
- Having a somatic pathology in particular neurological, endocrinal or blood circulation diseases (e.g., Raynaud's disease)
- Having personal or first-degree relatives' history of diagnosed psychiatric disorders (according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders - DSM5)
- Having psychotic prodomes measured by a score above 6 in the "prodomal questionnaire' - PQ-16 (Ising et al., 2012)
- Having developed musical abilities (that is, regularly practicing a musical instrument)
- Being pregnant or nursing