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Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment: A Feasibility Study

Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment: A Feasibility Study

Recruiting
18-75 years
All
Phase N/A

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Overview

The goal of this feasibility study is to test the safety and effectiveness of an high-intensity task oriented circuit training program, followed by three months of telerehabilitation in people with mild to moderate Multiple Sclerosis (MS). The main questions it aims to answer are:

  • Can high-intensity task oriented circuit training improve gait and balance functional capacity?
  • Can telerehabilitation mantain the benefits in gait and balance gained via circuit training for a six month period?

Participants will:

  • Complete 10 session ( one hour each, three times a week) of high-intensity task oriented circuit training administered in a hospital setting. The training will target key motor skills such as walking, stepping, supine to stand transitions and general mobility.
  • Engage in 3 months of asynchronous telerehabilitation (without physiotherapist supervision)

Eligibility

Inclusion Criteria:

  • Diagnosis of primary or secondary progressive multiple sclerosis according to the McDonald criteria.
  • Mini-Mental State Examination (MMSE) score > 24.
  • Expanded Disability Status Scale (EDSS) score ≤ 6.

Exclusion Criteria:

  • Presence of other psychiatric or neurological disorders.
  • Cardiopulmonary, renal, or liver diseases.
  • Pregnancy.
  • Modifications in drug treatment within the last 3 months.

Study details
    Multiple Sclerosis

NCT07058870

University Hospital of Ferrara

21 July 2025

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