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Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

Recruiting
18 years and older
All
Phase 1

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Overview

To provide a treatment of both actinic keratoses and photodamage within one treatment.

Description

To demonstrate that treatment of actinic keratoses and photodamage with a combination of Ameluz and Broad Band Light (BBL) will lead to an improvement in facial precancerous change and signs of photodamage.

Eligibility

Inclusion Criteria:

  • Over 18yrs of age
  • Willingness to participate in all required study activities and visits
  • Willingness to sign the informed consent form
  • Visible and palpable signs of diffuse actinic damage and actinic keratoses of mild to moderate severity located on the face
  • Significant signs of photoaging, evaluated by investigator, that include any or all the following:
    • Dyspigmentation
    • Solar lentigines
    • Telangiectasias
    • Diffuse erythema
    • Roughness and other textural changes
    • Fine lines
    • Wrinkles
    • Actinic bronzing

Exclusion Criteria:

  • Subject who is unable and unwilling to provide consent for study schedule and procedures
  • Subject who is pregnant or trying to become pregnant during the study
  • Subjects using any topical treatment on their AKs; must stop at least one month prior
  • Subjects currently undergoing cancer treatment with medical or radiation therapy
  • Subjects with a known hypersensitivity to 5-aminolevulinic acid or any component of the study material
  • Subjects with history of a photosensitivity disease, such as porphyria cutanea tarda

Study details
    Actinic Keratoses
    Photodamage

NCT07053852

Sherrif Ibrahim

9 August 2025

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