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CGM Dynamic Index for Predicting Prediabetes in Cystic Fibrosis

CGM Dynamic Index for Predicting Prediabetes in Cystic Fibrosis

Recruiting
12-55 years
All
Phase N/A

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Overview

The primary objective of this pilot study is to develop a CGM-based model to predict the progression from prediabetes to diabetes in individuals with cystic fibrosis.

Eligibility

Inclusion Criteria:

  • CF individuals aged 12-55 years.
  • CF without diabetes or with prediabetes (as defined by OGTT and HbA1c).
  • Willing to use a continuous glucose monitoring system with compatible smart phone for glucose data collection.

A person with CFRD and already using CGM, we will just collect their personal CGM data, and they are not required to have OGTT or HbA1c visit.

Exclusion Criteria:

  • Pregnancy.
  • History of transplant.
  • Use of immunosuppressant drugs.
  • Use of oral steroids or any medication known to interfere with glucose.
  • Allergy to adhesives.
  • Individuals with severe concurrent medical conditions that could confound glucose monitoring data (e.g., terminal illness, major organ failure).
  • Conditions that may make unsafe for participants to do study or impair or confound the study at the discretion of the investigator

Study details
    Prediabetes
    Cystic Fibrosis (CF)
    Cystic Fibrosis-related Diabetes

NCT06642610

Indiana University

10 July 2025

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