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Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

Recruiting
65-90 years
All
Phase N/A

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Overview

This study investigated the effect of Trendelenburg position on preventing post-induction hypotension in elderly patients undergoing abdominal surgery with general anesthesia. The patients will receive the 10° Trendelenburg position or supine position during anesthesia induction. The primary outcome is the area under a mean arterial pressure (MAP) below 65 mm Hg within the first 15 minutes during anesthesia induction.

Eligibility

Inclusion Criteria:

  • patients aged 65-90 years
  • scheduled for abdominal surgery with general anesthesia
  • expected to have continuous radial arterial pressure monitoring
  • American Society of Anesthesiologists (ASA) physical status I to III

Exclusion Criteria:

  • contraindications or failure of radial arterial catheterization
  • expected possible difficult airway
  • non-sinus rhythm
  • increased intracranial pressure
  • patients at high risk of regurgitation or aspiration
  • inability to provide consent

Study details
    Hypotension on Induction
    Old Age

NCT06968091

Zhejiang Cancer Hospital

8 July 2025

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