Overview
The study plans to enroll a total of 132 patients. The goal of this study is to measure pre-and post-music intervention changes in patients' vital signs, serum- and plasma-level biomarkers by broad-spectrum proteomics analysis, metabolic analysis, and perceived pain, anxiety, and mood states as measured by validated questionnaires (STAI-S, POMS-SF, and VASP). We will collect demographic information on each participant. Participants will also complete the Brief Musical Experience Questionnaire (BMEQ) to investigate potential links between susceptibility to music-induced anxiolysis and prior musical training, preference and exposure.
Description
Primary Objectives:
- To evaluate the effects of the two (live and recorded) prescribed preoperative containing CER on physiologic and perceived stress in patients undergoing Neurosurgery.
- To evaluate the effects of those two music interventions on serum- and plasma-level stress biomarkers and cytokines in those patients.
Secondary Objectives:
• To measure correlative effects of demographic variables, prior musical training, experience, preference, and exposure to music.
Eligibility
Inclusion Criteria
- Patients undergoing neurosurgical procedures will be eligible to enroll in this study.
Exclusion Criteria
- Patient is unable or unwilling to provide informed consent.
- Patient is deaf or hearing-disabled.
- Patient is less than 18 years in age.
- Patient was previously enrolled in the study.
- Non-English-speaking patients (patient must be fluent in English and not require translation services per MDACC institutional policy.
- Subjects on contact isolation precautions.