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A Phase I/II Study to Evaluate the Safety and Immunogenicity of GC3111B in Healthy Adults

A Phase I/II Study to Evaluate the Safety and Immunogenicity of GC3111B in Healthy Adults

Recruiting
19-64 years
All
Phase 1/2

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Overview

This clinical trial consists of two parts: Part 1, which explores safety, and Part 2, which examines both safety and efficacy (immunogenicity). Part 1 is a single-center, open-label, single-group study, while Part 2 is designed as a multicenter, double-blind, randomized, active-controlled trial.

Eligibility

Inclusion Criteria:

  • Healthy adults aged 19 to 64 years old as of the date of written consent.
  • Individuals with no history of vaccination with a vaccine containing diphtheria, tetanus, or pertussis antigens within the past 2 years prior to administration of the investigational product.

Exclusion Criteria:

  • Individuals who have received a vaccine within 4 weeks prior to administration of the investigational product.
  • Individuals with a history of Tdap vaccination prior to administration of the investigational product.
  • Pregnant and breastfeeding women.
  • Individuals who have participated in other clinical trials involving investigational products/devices within 6 months prior to administration of the investigational product.

Study details
    Tetanus-diphtheria-acellular Pertussis (Tdap)

NCT06997627

GC Biopharma Corp

20 July 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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