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Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)

Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)

Recruiting
65 years and older
All
Phase N/A

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Overview

The purpose of the study is to investigate whether an extended program (ERAS 3.0) initiated hospital discharge, can improve recovery in elderly, frail patients who have undergone surgery for colon cancer.

The study is a randomised controlled trial with two groups: an intervention group receiving the ERAS 3.0 program and a control group recieving standard care. The ERAS 3.0 program includes a comprehensive geriatric health assessment, dietary counseling from a dietitian, and instructions on training and physical activity. These activities will take place in the participant's homes after hospital discharge. Data will be collected at multiple time points: at the hospital, 12 days post-discharge (at the outpatient clinic), and at 1 and 3 months post discharge in the participants' homes.

Eligibility

Inclusion Criteria:

  • Age 65+
  • Clinical Frailty Scale preoperative score 4-7
  • Nutritional Risk Screening tool (NRS 2002) > 3
  • Elective colonic resection
  • No stoma planned
  • Minimally invasive surgical approach (laparoscopic or robotic)
  • Patients discharged to own home
  • Informed consent to participate

Exclusion Criteria:

  • Stoma creation during index surgery
  • Conversion to laparotomy
  • Major complications following surgery (Clavien-Dindo >3a)
  • Participation in other randomised trials in conflict with the protocol and endpoints of the ERAS 3.0 project
  • Discharged with tube feeding and parenteral nutrition (partially or completely)
  • Known food allergies to dairy or any other ingredient contained in the nutrition package
  • Incapable of providing informed consent
  • Discharge to 24-hour municipal rehabilitation facility
  • All conditions including psychological, geographical, and social factors that could hinder adherence to the trial protocol
  • Neoadjuvant radio- or chemotherapy

Study details
    Colon Cancer
    Frailty

NCT06802991

Copenhagen University Hospital at Herlev

17 June 2025

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FAQs

Learn more about clinical trials

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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