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Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis

Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis

Recruiting
20-40 years
All
Phase N/A

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Overview

This study was done to find out the effect of photobiostimulation and pulsed electromagnetic field in patients with chronic rhinosinusitis on:

  • Quality of life.
  • Pulmonary function.
  • Mean platelet volume.
  • headache .
  • total nasal symptoms.

Description

Chronic rhinosinusitis is a severe disease that significantly impacts a patient's quality of life, leading to significant economic impacts on healthcare resources and absenteeism. Symptoms interfere with daily activities and can lead to medication resistance. Treatment options like steroids, oral antibiotics, and sinus surgery are less effective, and disease recurrence remains high even after surgery. Alternative therapies like low-level laser therapy and pulsed electromagnetic filed have shown promise in improving symptoms and potentially making low-level laser therapy a non-invasive treatment for Chronic rhinosinusitis

Eligibility

Inclusion Criteria:

  1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9).
  2. Subjects age range from 20 to 40 years old.
  3. Patients of both sexes.
  4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months

Exclusion Criteria:

  • Pregnant or breastfeeding women.
  • Patients with a definite deviated nasal septum, or history of operation within the last 6 months.
  • Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases.
  • Long-term use of corticosteroids or immunosuppressive agents.
  • Participation in another clinical study within 30 days.
  • Hyperthyroidism
  • Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate.
  • Patients with Tattoos, moles and dark skin

Study details
    Photobiostimulation
    Pulsed Electromagnetic Filed
    Low Level Laser Therapy
    Chronic Rhinosinusitis (Diagnosis)
    Quality of Life

NCT06986629

Cairo University

5 June 2025

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