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A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs

A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs

Recruiting
18 years and older
All
Phase N/A

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Overview

The study compares the effectiveness of three commercial weight management programs. The primary outcome is absolute and percentage weight change at 12-weeks.

Eligibility

Inclusion Criteria:

  • 18 years or older
  • BMI ≥27 kg/m²
  • Own a bodyweight scale that they can weigh themselves with during the study
  • Willing and able to comply with study protocol
  • Capable of providing informed consent
  • Able to read and write in English
  • Willing to be randomized
  • Willing to sign a Non Disclosure Agreement

Exclusion Criteria:

  • Pregnant, lactating, or plans to become pregnant in the next 6 months
  • Previous bariatric surgery or planned bariatric surgery during the study period
  • Major surgery within the past 6 months or plans to have surgery during the study period
  • Participation in the previous 3 months or current participation in a structured behavioral weight loss program
  • Participation in another structured weight loss program during the study period (i.e., the next 3 months)
  • Communication needs that would render them unable to understand the study and/or intervention materials
  • Current or previous history of anorexia or bulimia nervosa
  • Engagement with vomiting or laxative use within the last 28 days with the aim of controlling their shape or weight
  • Currently taking anti-obesity medications, planning to take anti-obesity medications in the next 6 months, or previously taken anti-obesity medications in the previous 3 months
  • Weight loss of ≥ 5 kg (11 lb) in the previous 6 months
  • Self-reported diagnosis of severe depression, bipolar disorder, substance abuse, or psychosis
  • Participants who are involved in any other research studies at this time
  • Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
  • Chronic/inflammatory gastrointestinal disorders (irritable bowel syndrome is acceptable)
  • History of heart problems (e.g., angina, bypass surgery, myocardial infarction, etc.) within previous 6 months
  • Diagnosis of type 1 or type 2 diabetes
  • Presence of implanted cardiac defibrillator or pacemaker
  • History of cancer within past 5 years or current treatment for cancer
  • Hospitalization for psychiatric disorders during the last 12 months

Study details
    Obesity and Overweight

NCT06972277

WW International Inc

2 June 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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