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Bipolar Resection vs Enucleation of Prostate

Bipolar Resection vs Enucleation of Prostate

Recruiting
50-80 years
Male
Phase N/A

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Overview

The aim of this study is to evaluate efficacy and safety of transurethral resection of the prostate and bipolar enucleation of the prostate.

Description

Endoscopic management of benign prostatic hyperplasia (BPH), monopolar transurethral resection of the prostate (TURP) has been the gold standard for many years.

Despite its promising efficacy in treating BPH, TURP is associated with a risk of significant complications and clinical limitations, including life-threatening events such as transurethral resection (TUR) syndrome, as well as high cost due to long hospital stay, long catheterization time and difficulty in management of large sized prostate so alternative surgical approaches have been explored.

Minimally invasive approaches achieve equal efficiency to standard resection, but with a more favorable safety and less complications.

Anatomical enucleation of the prostate using Bipolar or Laser-based approaches such as holmium laser have been introduced with success and the efficacy and safety of these procedure has led to the integration into several international guidelines.

Early results of bipolar enucleation resemble those reported for holmium laser procedure, Bipolar transurethral enucleation of the prostate was at least equally effective, and showed less complications, good hemostatic control and both shorter catheterization time and hospital stay than old standard procedure.

A comparison between TURP and Bipolar enucleation of prostate allows us to investigate the true benefits and safety of each modality.

Eligibility

Inclusion Criteria:

  1. Patients with lower urinary tract symptoms (LUTS) due to BPH.
  2. Patients with international prostate score system (IPSS) more than 8.
  3. Patients with maximal urinary flow rate (Qmax) less than 10ml/second.
  4. Patients with Prostatic volume (60 - 100 gm).
  5. Patient with indication for surgical intervention.
  6. Patient age (50-80 years old)

Exclusion Criteria:

  1. Prostatic cancer.
  2. Bladder cancer.
  3. Urethral stricture.
  4. Neurogenic bladder.

Study details
    Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection
    Benign Prostatic Hyperplasia With Outflow Obstruction
    Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms
    Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms

NCT06983444

South Valley University

26 May 2025

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