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A Phase 1 Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers

A Phase 1 Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers

Recruiting
18-65 years
All
Phase 1
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Overview

The purpose of this study is to evaluate the safety and tolerability of single ascending doses of ALN-4324 in healthy volunteers and to characterize the single-dose PK of ALN-4324.

Eligibility

Inclusion Criteria:

  • Has a body mass index (BMI) of ≥27 kg/m^2 and <40 kg/m^2

Exclusion Criteria:

  • Has known human immunodeficiency virus (HIV) infection; or known current or chronic hepatitis C virus or hepatitis B virus infection

Note: other protocol defined inclusion/exclusion criteria apply

Study details
    Obese or Overweight Healthy Volunteers

NCT06845202

Alnylam Pharmaceuticals

16 May 2025

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FAQs

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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