Overview

The aim of this clinical trial is to compare the outcomes of open versus laparoscopic repair for perforated peptic ulcer and provide evidence-based guidance to the selection of the most appropriate operative technique at Sohag University Hospital. The study will include patients presented with perforated peptic ulcers as a complication of peptic ulcer disease during the period of study.

Eligibility

Inclusion Criteria:

• All patients with a clinical diagnosis of perforated peptic ulcer that are fit to undergo surgery either via laparotomy or laparoscopy, males or females, any age, with gastric or duodenal ulcer, with American Society of Anesthesiologists (ASA) grade I, II, III.

Exclusion Criteria:

• Patients with associated bleeding ulcer (additional steps are needed to control bleeding).
• Patients with associated pathology other than perforated peptic ulcer.
• Patients with American Society of Anesthesiologists (ASA) grade IV, V, VI.