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Establishment of a Longitudinal Cohort for Newborns With Low Apgar Scores at Birth

Establishment of a Longitudinal Cohort for Newborns With Low Apgar Scores at Birth

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Phase N/A

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Overview

The objective of this study is to identify high-risk factors associated with low Apgar scores, implement proactive interventions to reduce their occurrence, and analyze neonatal resuscitation procedures and systemic treatment during hospitalization. This aims to provide evidence-based references for improving the resuscitation and medical management of newborns with low Apgar scores, thereby enhancing clinical care capabilities. Additionally, continuous follow-up management and timely intervention guidance will be provided to these infants to optimize their long-term prognosis.

Description

This is a prospective and retrospective biphasic cohort study.Retrospective cohort inclusion criteria: Newborns born between January 1, 2006 and before the start of the project at Peking University Third Hospital with Apgar scores ≤ 7 at 1 minute, 5 minutes, or 10 minutes.

Prospective cohort inclusion criteria: Newborns born in our hospital between the start of the project and December 31, 2027, with an Apgar score of ≤ 7 at 1 minute, 5 minutes, or 10 minutes.

Eligibility

Inclusion Criteria:

  • Retrospective cohort inclusion criteria: Newborns born between January 1, 2006 and before the start of the project at Peking University Third Hospital with Apgar scores ≤ 7 at 1 minute, 5 minutes, or 10 minutes.

Prospective cohort inclusion criteria: Newborns born at Peking University Third Hospital between the start of the project and December 31, 2027, with an Apgar score of ≤ 7 at 1 minute, 5 minutes, or 10 minutes.

Exclusion Criteria:

  • There are serious congenital malformations that affect physical and neurological development, and family members refuse to participate in the study

Study details
    Low Apgar Scores

NCT06961123

Peking University Third Hospital

11 May 2025

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