Overview
There are currently no clinical and laboratory data that well characterize this neutropenia associated with the Duffy-null phenotype, particularly for pediatric subjects. In particular there are no data on the frequency of immune neutropenia in DANC neutropenic pediatric subjects.
The goal of this study is to :
- define the frequency of immune neutropenia within the cohort of DANC subjects under study
- evaluate the frequency of different degrees of neutropenia (mild-moderate-severe);
- evaluate the possible association between different degrees of neutropenia and the presence of infections.
Eligibility
Inclusion Criteria:
- presence of Duffy-null phenotype
Exclusion Criteria:
- absence of Duffy-null phenotype