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Evaluation of Long-term Isokinetic Training of Knee Joint

Evaluation of Long-term Isokinetic Training of Knee Joint

Recruiting
20-60 years
All
Phase N/A

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Overview

The goal of this clinical trial is to assess the effectiveness of isokinetic rehabilitation training under optimal stiffness in patients undergoing knee joint rehabilitation. The main questions it aims to answer are:

  • Does isokinetic training under optimal stiffness lead to greater force exertion compared to traditional bodyweight training?
  • What are the long-term (6-week) effects of isokinetic training under optimal stiffness on joint flexibility and muscle strength? Researchers will compare the effects of isokinetic training under optimal stiffness to traditional bodyweight training to see if isokinetic training produces superior improvements in muscle strength, flexibility, and overall functional recovery.

Participants will:

  • Perform regular training sessions using a portable knee joint isokinetic trainer, customized to their optimal stiffness for maximum force exertion.
  • Engage in a 6-week rehabilitation program, with assessments at the beginning, and end of the study to evaluate changes in muscle strength, and functional recovery.

Eligibility

Inclusion Criteria:

  1. Age between 20-60 years.
  2. Patients with unilateral anterior cruciate ligament (ACL) rupture, with or without meniscus injury.
  3. Postoperative period of 3-6 months.
  4. No restriction in knee extension or flexion movements.

Exclusion Criteria:

  1. Patients with major diseases or conditions such as coronary heart disease, myocardial infarction, heart failure, cerebral infarction, cerebral hemorrhage, or malignant tumors.
  2. Pregnant or breastfeeding women and other special populations.
  3. Patients who refuse to sign the informed consent form or are unable to complete the entire study process.
  4. Patients currently infected with human immunodeficiency virus (HIV), or with a history of infectious hepatitis B or C.
  5. Patients with concurrent medical issues, including but not limited to: (1) Uncontrolled hypertension (systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥95 mmHg), congestive heart failure (New York Heart Association functional classification of stage III or IV). (2) Patients with mental incapacity or an inability to comprehend the study requirements.

Study details
    Knee Injuries and Disorders

NCT06674473

Peking University Third Hospital

2 May 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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