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Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

Recruiting
18-89 years
All
Phase N/A
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Overview

The purpose of this research study is to explore whether genetic testing can offer a personalized and timely approach to assist physicians in making more informed medication decisions for stroke or high-risk transient ischemic attack (TIA) patients during their hospital stay.

Description

This is a pilot clinical trial for feasibility

Eligibility

Inclusion Criteria:

  • Patients 18-89 years of age
  • admitted to University of Alabama at Birmingham (UAB) main hospital with symptoms or signs of minor ischemic stroke, or high risk TIA
  • eligible to receive dual antiplatelet load (presented to the hospital within 66 hours of last known well)

Exclusion Criteria:

  • diagnosis of atrial fibrillation, valvular heart disease, index stroke due to known hypercoagulability (subset of other determined etiology) or large vessel disease (culprit vessel stenosis of ≥50%)
  • prescribed anticoagulation prior to stroke
  • treated with intravenous thrombolysis
  • treated with mechanical thrombectomy
  • missing NIH Stroke Scale score

Study details
    Stroke
    Transient Ischemic Attack (TIA)

NCT06943586

University of Alabama at Birmingham

8 May 2025

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