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COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs).

Participants will:

  • undergo pupillary dilation
  • have photographs taken of the inside of the eyes using three different cameras

Eligibility

Inclusion Criteria:

  • Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial
  • Participants that are willing to participate as evidenced by signing the written informed consent

Exclusion Criteria:

  • Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation
  • Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring
  • Patients with advanced IRDs who are unable to fixate for imaging
  • Patients unable to tolerate ocular imaging
  • Patients who do not wish to participate

Study details
    Retinal Disease

NCT06380075

University of Wisconsin, Madison

5 May 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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