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the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome

the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome

Recruiting
18-40 years
Female
Phase 2
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Overview

Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval. endometrial receptivity parameters, including the subendometrial vasculature indices were measured before and after the intervention for purpose of studying the effect of hyaluronic acid on improvement of the endometrial receptivity and subsequently the pregnancy outcome

Eligibility

Inclusion Criteria:

  • Infertile females aged 18-40 years.
  • Infertile females scheduled for GnRH antagonist protocol of fresh ICSI cycle.
  • Females use dual stimulation (GnRH agonist plus Ovetrelle) for ovulation triggering.

Exclusion Criteria:

  • Infertile females diagnosed as a poor responder.
  • Infertile females diagnosed with uterine pathology.
  • Infertile females who are scheduled for a frozen ICSI cycle.
  • Infertile females diagnosed with endocrine diseases like thyroid disease, diabetes mellitus, and hyperprolactinemia.
  • Infertile females diagnosed with thrombocytopenia.

Study details
    Infertile Patients

NCT06937645

Al-Nahrain University

25 April 2025

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