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Developing and Testing an Online Pathway From Screening to Treatment for Depression in Oncology: iPath*D (Aim 2)

Developing and Testing an Online Pathway From Screening to Treatment for Depression in Oncology: iPath*D (Aim 2)

Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to determine the extent to which an online pathway to depression treatment (iPath*D) is acceptable and usable to patients receiving cancer treatment who report symptoms of depression.

Description

The investigators will determine the extent to which an online pathway to depression treatment (iPathD) is acceptable and usable to patients receiving cancer treatment who report symptoms of depression. iPathD will be designed to increase screening, mental health literacy, and treatment access. Patients will access their iPath*D account online to review their PHQ-9 score and its interpretation, followed by an interactive depression decision aid comparing information on a range of online and in-person treatment options. Upon review of the decision aid, participants will be able to directly connect to a treatment path via embedded hyperlinks in the decision aid.

The investigators will determine the usability, acceptability, and feasibility of iPathD. The investigators will explore the hypothesis that iPathD will be highly usable, acceptable to patients, feasible to implement, and will result in improved mental health literacy, and greater treatment access. The tool for the study was developed during a preliminary portion (Aim 1) of the project, under D-H IRB number STUDY02001240 .

This approach uses an open-label, single arm pilot, with adult patients receiving treatment for cancer in a rural cancer clinic, St Johnsbury, VT (Dartmouth Cancer Center North) (n=30) with moderate-severe depression, Aim 2 of the project.

Eligibility

Inclusion criteria

  1. Adults (≥18 years)
  2. New patients who are beginning treatment at Dartmouth Cancer Center North and returning for their chemo teach or radiation simulation visit
  3. Can communicate in English
  4. PHQ-9 ≥10 and ≤27

Exclusion criteria

  1. Mild Depression (PHQ-9 ≥10)
  2. Individuals who screen positive for suicidal ideation with method, intent, plan or a recent prior suicide/self-harm attempt, as determined by a positive endorsement of items 3, 4, 5 or 6 on the Columbia-Suicide Severity Rating Scale (C-SSR).
  3. Individuals with bipolar disorder or psychosis (documented in the EMR)
  4. Individuals currently receiving treatment for a mental health condition (documented in the EMR or self-reported during eligibility screening)
  5. Significant cognitive impairment (Callahan's Six Item Screener of cognitive function ≤ 4; Self-reported during eligibility screening)

Study details
    Cancer
    Depression

NCT05302375

Dartmouth-Hitchcock Medical Center

16 April 2025

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