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Study of ZG005 Combined With Bevacizumab Versus Sintilimab Combined With Bevacizumab in Advanced Hepatocellular Carcinoma

Recruiting
18 - 75 years of age
Both
Phase 2
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Overview

This study is a randomized, open-label, positive-controlled, multicenter phase II clinical trial. It evaluates the efficacy and safety of ZG005 combined with Bevacizumab compared to Sintilimab combined with Bevacizumab in first-line treatment for patients with advanced hepatocellular carcinoma.

Eligibility

Inclusion Criteria:

  • Fully understand the study and voluntarily sign the informed consent form.
  • 18-75 years of age;
  • Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1；
  • Life expectancy ≥ 12 weeks.

Exclusion Criteria:

  • Patients were deemed unsuitable for participating in the study by the investigator for any reasons.

Study details

Hepatocellular Carcinoma

NCT06558227

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

29 March 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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