A Study Conducted to Evaluate the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and in Participants With Neovascular Age-related Macular Degeneration (nAMD)/Diabetic Macular Edema (DME)

Overview

The purpose of this study is to obtain conjunctiva and tenon's capsule thickness measurements in vivo using spectral domain-optical coherence tomography (SD-OCT) in participants with nAMD/DME and age-matched healthy subjects.

Eligibility

Inclusion Criteria:

For nAMD/DME participants:

• Diagnosis of nAMD/DME

For healthy subjects:

• Normal visual function

Exclusion Criteria:

• Current or past treatment for glaucoma (only for healthy subjects)
• Dry eye disease except those treated only with artificial tears
• Ocular hypertension treated with hypotensive drugs
• Pterygium
• Strabismus
• Previous ocular surgery except cataract surgery
• Cataract surgery with scleral incision
• Current contact lens wearers
• Myopia with more than 6 diopters
• Corneal transplant
• History of ocular surface inflammation
• Active or recent conjunctivitis infection
• Pregnancy
• Participant who has already received an IVT injection in the superotemporal quadrant (only for nAMD/DME participants)